“ESTIMATION OF RADICAL SCAVENGING POTENTIAL OF SELECTED MEDICINAL PLANTS OF LAHORE, PAKISTAN”


 In the current research, in vitro antiradical potential of some medicinal trees Lahore, Pakistan was investigated. Various fruits and pods 25 plants (Prosopis juliflora, Carissa carandas, Ceiba speciosa, Heterophragma adenophyllum Cestrum diurnum Jacaranda mimosifolia, Diospyros malabarica, Terminalia bellerica, Ficus lyrata, peregrine, Cinnamomum verum, Erysimum cheiri, Buchanania lanzan, Withania somnifera, Fagonia arabica, Berberis lycium, Strychnos potatorum, Matthiola incana, Ziziphora tenuior, Centaurea behen, Rosa indica, Punica granatum, Lodoicea maldivica, Cassia absus, Celastrus paniculatus) were extracted by ethanol. Different concentrations fruit extracts (1, 0.5, 0.25, 0.125 mg/mL) prepared to evaluate antioxidant activity. The DPPH (2,2-diphenyl-1-picrylhydrazyl) free radical scavenging method performed compared with standards like Vitamin E, BHT (Butylated hydroxytoluene) ascorbic acid. Many plant exhibited 80% F. Arabica, S. M. P. C. W. T. H. showed significant anti-radical (98.4±0.52, 96.40±0.52, 96.42±0.51, 94.58±0.52, 94.47±0.50, 94.65±0.56, 94.55±0.50, 91.42±0.51% inhibition, respectively) at 1 mg/mL equivalent i.e. acid inhibition (88.25±0.2, 78.1±0.3 40.51±0.17%), respectively. Moreover, dose dependent activity observed as decline percentage lower concentration. 50% inhibitory concentration (IC50) also determined for that varied from 0.014± 0.001 (W. somnifera J. mimosifolia) 2.69±0.001 (B.lanzan) depending on sample extracts. natural antioxidants may be used foods products a substitute synthetic antioxidants, which have side effects.